Osteosarcomas rarely affect the jawbones, and are challenging to diagnose and treat. We report a case of a 23-year-old male patient, admitted to the medical emer gency service due to edema located in the left mandibu lar region. Patient denied comorbidities and known aller gies, an oral panoramic radiograph was performed, which exposed radiopacity in sunlight, a pathognomonic sign of osteosarcoma as demarcation in red highlights (Fig. 1). On intra-oral clinical examination, the lesion presented exophytic characteristics, necrotic aspect and edges with hardened consistency as indicated by the red arrow.

Figure 1 

The patient was referred to the head and neck surgery team, which requested a computed tomography to assess the extent of the lesion, where it was possible to observe in the sagittal, coronal and axillary sections the large dimen sions that the tumor presented and the level of structural impairment (Fig. 2 A, B and C). After confirming the diag nosis, he resected the tumor and started radiotherapy and chemotherapy. This case is the first treated and documen ted in the country’s unified health system. Patient followed between 2019 and 2021. In August 2021, the patient died due to complications arising from the tumor.

Figure 2