Abstract

LORENZO VILLALBA, Noel et al. Acquired hemophilia as the initial manifestation of colorectal cancer’s recurrence. Medicina (B. Aires) [online]. 2021, vol.81, n.2, pp.286-288. ISSN 0025-7680.

We report the case of an 86-year-old man presenting with a spontaneous hematoma in the left iliac muscle and previous diagnosis of colon cancer in 1998 (stage pT3N0M0) treated with transverse colectomy and considered in complete remission. After a complete study, it was possible to identify the presence of Factor VIII inhibitors antibodies that confirmed the presence of acquired hemophilia. During hospitalization the patient presented a lower gastrointestinal bleeding leading to the diagnosis of recurrence of a previously treated colorectal adenocarcinoma. He responded to initial therapy with systemic corticoids and anti-inhibitory coagulant complex which includes activated VII Factor [FEIBA].

Keywords : Spontaneous hematoma; Acquired hemophilia; Anti Factor VIII antibodies.

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