Services on Demand
Journal
Article
Indicators
- Cited by SciELO
Related links
- Similars in SciELO
- uBio
Share
Acta bioquímica clínica latinoamericana
Print version ISSN 0325-2957On-line version ISSN 1851-6114
Abstract
LAZARTE, Sandra; LERI DE NOFAL, Mónica; AGUERO, María Graciela and ISSE, Blanca. Hematological profile of b-thalassemia minor in Tucuman. Acta bioquím. clín. latinoam. [online]. 2007, vol.41, n.2, pp.219-223. ISSN 0325-2957.
The b-thalassemia minor is one of the most common genetic blood disorder and it represents the main cause of hereditary anemia. There is scant information in the scientific literature about b-thalassemia minor distribution in Argentina, except for the provinces of Buenos Aires and Santa Fe. There is no published study of this disorder in the northwest of Argentina. The objective of this descriptive and explorative study is to determine the hematological and electrophoretic characteristics of a b-thalassemia minor population in the province of Tucumán. A total of 52 patients with suspected thalassemia syndrome were studied; haemogram, reticulocytes, serum iron, hemoglobin electrophoresis, hemoglobin F and hemoglobin A2 were performed. Forty-six percent of the patients presented a b-thalassemia minor diagnosis, with the following findings: mild anemia with microcytosis and elevated Hb A2. The hematological profile showed no significative differences with respect to age and sex, and it was similar to previous studies, published by different authors. The ethnic origins were as follow: Italians 58%, Spaniards 34% and Arabians 8%, with preponderance of the Italian population, similar to previous studies in Argentina.
Keywords : hereditary anemia; thalassemia syndrome; b-thalassemia minor; microcytosis.