Abstract

BENHAIM VARELA, Marcela Estela et al. Metabolic study in patients with non-alcoholic fatty liver disease. Acta bioquím. clín. latinoam. [online]. 2016, vol.50, n.1, pp.11-16. ISSN 0325-2957.

A group of thirty patients with non-alcoholic fatty liver has been clinically followed up in the Gastroenterology Unit of Eva Perón Hospital, Buenos Aires, Argentina. Values of glucose, ALAT, ASAT, insulin, HOMA index, inflammatory markers and leptin were measured in all the cases and their findings have been correlated with the clinical aspects. All the patients had partial or complete metabolic syndrome. The populational averages of insuline, HOMA index, PCR and leptine were higher than those considered normal ranges. These higher levels were statistically significant in all cases. An increased risk of coronary disease was observed in 52% of the cases, while 16.6% of the patients showed hepatic cirrhosis. As all the patients with non-alcoholic fatty liver had partial or complete metabolic syndrome; it is proposed that the presence of fatty liver disease be searched in patients with metabolic syndrome as it is usually done to prevent other usual complications, such as retinopathy, nephropathy, neuropathy or cardiovascular disease.

Keywords : Non alcoholic fatty liver; Metabolic syndrome; Insulin resistance; Inflammation; Leptine.

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