Abstract

BOCIO, Cleo Irene et al. Comparación de dos tipos de recipientes para analizar gases en sangre y otras mediciones relacionadas contra jeringas con heparinato de litio liofilizado. Acta bioquím. clín. latinoam. [online]. 2020, vol.54, n.2, pp.117-124. ISSN 0325-2957.

Blood gas analysis involves tests related to the acid-base balance and oxygenation state (pH, pO₂, SO₂, pCO₂, HCO₃ -). In multiparametric equipment, some ion and metabolite (related measurements) are performed: Na+, K⁺, Cl^-, Ca²⁺, glucose and lactate. The objective of this study was to compare two types of containers (type 2: syringe prepared in the laboratory with diluted liquid sodium heparinate and type 3: microtube with liquid lithium heparinate) against the container recommended by CLSI in its guide 46-A2 (type 1: syringe with lyophilized lithium heparinate balanced with inc). The analysis was made from a statistical and clinical point of view to establish the possibility of indiscriminately using these three types of containers. A total of 254 samples were analyzed. To establish the clinical acceptance of the results, the biological variability quality standard was used. No clinically significant differences were found in the analytes of the type 2 container compared to type 1, except for Ca+. Several analytes of the type 3 container were rejected from the clinical point of view. In conclusion, the use of the type 3 container is inappropriate; however, the type 2 container would be suitable for the analysis of this type of samples.

Keywords : Blood gas analysis; Pre-analytical quality; Lyophilized lithium heparinate; Liquid Na⁺ heparinate; Ionic calcium.

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