Abstract

CORSO, A.  and  ARGENTINEAN SIREVA WORKING GROUP et al. Prevalence of mef and ermB genes in invasive pediatric erythromycin-resistant Streptococcus pneumoniae isolates from Argentina. Rev. argent. microbiol. [online]. 2009, vol.41, n.1, pp.29-33. ISSN 0325-7541.

During the period 1993-2001, a total of 1,499 pneumococci isolates were recovered through the Argentinean surveillance of Streptococcus pneumoniae causing invasive disease in children under 6 years of age, 3.5% of which were erythromycin resistant. Among the 50 erythromycin-resistant strains available, 58% (n=29) harbored mefA/E genes (15 mefA, 30%; and 14 mefE, 28%), 34% (n=17) ermB, and 6% (n=3) both mefA/E plus ermB genes, while one isolate was negative for all the acquired genes studied. The England¹⁴-9 (42%), Poland^6B-20 (20%) and Spain^9v-3 (16%) clones were responsible for the emergence of pneumococcal macrolide resistance in pediatric population from Argentina.

Keywords : Streptococcus pneumoniae; Macrolide; Argentina; Mef; erm.

        · abstract in Spanish     · text in English     · English ( pdf )