Abstract

MAJUL, Claudio R et al. La intolerancia a la glucosa aumenta el índice de masa ventricular izquierda y la distensibilidad arterial en un grupo de hipertensos leves de sexo masculino. Rev. argent. cardiol. [online]. 2005, vol.73, n.6, pp.429-432. ISSN 1850-3748.

Glucose Intolerance Increases Left Ventricular Mass Index And Arterial Stiffness In Males with Mild Hypertension The aim of this study was to evaluate if a group of mild hypertensive males with glucose intolerance and central obesity, meeting metabolic syndrome (MS) criteria, presented greater left ventricular mass index and altered arterial compliance compared to a group of mild hypertensive males with central obesity but without glucose intolerance or MS. Fifty six male patients of 51±6 years of age were included and separated into two groups: A)28 with metabolic syndrome (ATP III): fasting blood sugar ≥1.10 g/l and < 1.26 g/ l or oral glucose tolerance test >1.40 g/l and < 2 g/l, waist circumference >102 cm and blood pressure ≥ 130/85 mmHg. B)28 patients without metabolic syndrome: fasting blood sugar < 1.10 g/l and oral glucose tolerance test < 1.40 g/l, and similar waist circumference and blood pressure as those in group A. Two-dimensional echocardiography was used to assess left ventricular mass index. Arterial compliance was measured by augmentation index and pulse wave velocity by Sphygmocor. Conclusion The association of mild hypertension and glucose intolerance leads to greater LVMI and arterial stiffness compared to non glucose intolerant hypertensive males.

Keywords : Diabetes mellitus; Metabolism; Hypertension; Arteries; Compliance.

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