Abstract

ALONSO RODRIGUEZ, Dalyla; PEDROSO FILIBERTO, Eduardo; MORENO TELLEZ, Ela  and  ACOSTA VALDEZ, María A.. Oxidative Stress in Cyanotic Congenital Heart Disease. Rev. argent. cardiol. [online]. 2007, vol.75, n.3, pp.189-190. ISSN 1850-3748.

Heart diseases and acute myocardial infarct are processes where free radicals are present in the pathophysiology, causing severe damage to myocardial structure and involving a cascade of events associated with membrane integration loss. Aimed at assessing the presence of oxidative stress in cyanotic congenital heart disease in a group of 20 pediatric patients with this condition, serum levels of antioxidatives such as albumin, ceruloplasmin, vitamin C, bilirubin, uric acid, and LDLox as oxidative damage marker were assessed. Results showed low levels of vitamin C, hyperbilirubinemia, and hyperuricemia; albumin and ceruloplasmin levels remained stable unlike LDLox, which showed the presence of oxidative stress in these patients.

Keywords : Congenital Heart Disease; Oxidative Stress; Free Radicals.

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