Abstract

ALONSO RODRIGUEZ, Dalyla; PEDROSO FILIBERTO, Eduardo; MORENO TELLEZ, Ela  and  ACOSTA VALDEZ, María A.. Lipidic Profile in Children with Cyanotic Congenital Heart Disease. Rev. argent. cardiol. [online]. 2007, vol.75, n.3, pp.191-192. ISSN 1850-3748.

Lipoprotein oxidation plays an important role in atherogenesis and endothelial damage, therefore in heart disease. In order to assess the lipidic profile in children with cyanotic congenital heart disease, determinations of HDL, LDL, total cholesterol, triglycerides, and oxidative LDL (LDLox) were assessed in a group of 20 children with this condition. Results were compared with those of a control group formed by 50 children supposedly healthy. It was shown that LDL oxidation is associated to the degree of oxidative stress in 100% of the ill patients, with elevated levels of LDL cholesterol (65%) and low levels of HDL cholesterol (70%), which makes the endothelium more sensitive to atherogenesis.

Keywords : Congenital Heart Disease; Oxidation; Lipoproteins.

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