Abstract

PEREZ-ELIZONDO, AD. Cutaneous coccidiodomycosis: Clinical image. Rev. argent. dermatol. [online]. 2017, vol.98, n.4, pp.1-10. ISSN 1851-300X.

Coccidiodomycosis is an uncommon systemic mycosis caused by the dimorphic fungi of the genus Coccidiodes, immitis and posadasii, whose arthroconidia generally infects humans via the respiratory system. Thanks to the proper functioning of the cellular immune system, most infections are self-limiting; in cases of immunodeficiency there may be disseminated and serious progressive forms that endanger the life of the affected patient. The diagnosis is based on the clinical findings, the observation and culture of different tissue samples through mycological and anatomopathological analysis; of particular help represent serological tests by demonstrating specific antibodies, such as: agar gel immunodiffusion and  complement  fixation, if  available.  Treatment  with  systemicazoles have been shown to be effective; similarly, amphotericin-B in intravenous administration with its known nephrotoxic effects is indicated especially in severe patients.

Keywords : systemic micosis; coccidiodomycosis; itraconazole.