Abstract

BALBONI, C; KIM, H; CABRAL, A Rodriguez  and  STELLA, I. ATYPICAL GRANULOMA ANNULARE¿ONLY A BENIGN ENTITY?. Rev. argent. dermatol. [online]. 2019, vol.100, n.4, pp.81-90. ISSN 1851-300X.

Granuloma annulare is a benign cutaneous inflammatory disease. It is usually asymptomatic and self-limited.

While the exact pathophysiology is unknown, it has been associated with a retarded hypersensitivity of type IV driven by the presence of unspecified antigens. Classical cutaneous lesions are characterized by the presence of papules coalescing to form annular plaques with a central clearing or a central depression.The clinical manifestations vary from a usual localized form to a generalized one, both with erythematous, violaceous or skin-colored lesions.

Given that most cases present the classical form, they do not pose a diagnostic challenge. However, histopathological study is necessary in the case of atypical clinical presentations. A 41-year-old male presented with a 4-month dermatosis.

The physical examination showed four 2cm erythematous plaques, slightly infiltrated in the right upper limb and three lesions of 1cm in the left upper limb with the same characteristics. Tactile, pain and thermal sensitivity was conserved. The patient only referred to an occasionally mild pruritus.

Keywords : Atypical Granuloma annulare; Localized Granuloma annulare; Collagen degeneration.

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