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Medicina (Buenos Aires)
versión impresa ISSN 0025-7680
Resumen
DAL VERME, Agustín et al. Secreción ectópica de ACTH en un paciente con antecedentes de enfermedad de Cushing. Medicina (B. Aires) [online]. 2015, vol.75, n.4, pp.218-220. ISSN 0025-7680.
A 54-year-old man, with a history of Cushing’s disease diagnosed 32 years earlier, presented with edema, asthenia and general malaise. Abnormal laboratory studies depicted hypokalemia and metabolic alkalosis. A CT scan of the chest revealed a 3 × 3 cm tumor in the anterior mediastinum. The pathology was consistent with a thymic carcinoid. These findings led to a diagnosis of biochemical Cushing’s syndrome secondary to ectopic secretion of ACTH. Thus, this patient suffered twice of Cushing’s syndrome. The first instance was the consequence of an ACTH - secreting pituitary adenoma and the second of an ectopic secretion of ACTH. To the best of our knowledge this is the first such case reported in the medical literature.
Palabras clave : Cushing’s disease; Ectopic secretion of ACTH; Thymic carcinoid.