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Medicina (Buenos Aires)
versión impresa ISSN 0025-7680versión On-line ISSN 1669-9106
Resumen
RODRIGUEZ ARIAS, Edwin A. et al. Nicolau syndrome. Medicina (B. Aires) [online]. 2023, vol.83, n.1, pp.145-148. ISSN 0025-7680.
Nicolau syndrome is a rare complication of the parenteral application of various drugs. It is char acterized by the appearance of pain, followed by edema, erythema, and then a necrotic plaque. We present the case of a 31-year-old male with this syndrome, after the application of intramuscular benzathine penicillin. The diagnosis was supported by the biopsy. He received treatment with enoxaparin and cilostazol with subsequent improvement.
Palabras clave : Nicolau syndrome; Drug skin embolism; Livedoid dermatitis; Penicillin; Adverse effect.