Resumen

JIAO, F. P.; CHEN, X. Q.; YANG, L.  y  HU, Y. H.. Enantioselective extraction of mandelic acid enantiomers using ester alcohol L-tartarate as chiral selector. Lat. Am. appl. res. [online]. 2008, vol.38, n.3, pp.249-252. ISSN 0327-0793.

Distribution behavior of mandelic acid enantiomers was examined in an aqueous-organic solvent of a two-phase system containing L-tartarate. The influences of pH, length of alkyl chain of L-tartarate, organic solvent, concentration of phosphate salt and time of chiral extraction on partition coefficient (k) and separation factor (α) were investigated, respectively. With the rise of pH, k decreases, but α increases. With the addition of length of alkyl chain of L-tartarate, k and α decrease. The organic solvent and concentration of phosphate salt also have a bigger influence on k and α. A new binary chiral selector system is presented, effective for the enantioselective extraction of racemic mandelic acid. The distribution coefficients of D- and L-mandelic acid as high as 14.9 and 7.0, respectively, and the enantioselectivity value of 2.1 were found.

Palabras clave : Mandelic Acid Enantiomers; L-Tartarate; Chiral Extraction; Binary Chiral Selector.

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