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Revista argentina de endocrinología y metabolismo
versión On-line ISSN 1851-3034
Resumen
ANGELINI, J. et al. Possible pathogenic correlation between dyslipemia and dysglycemia. Rev. argent. endocrinol. metab. [online]. 2018, vol.55, n.2, pp.6-10. ISSN 1851-3034.
Aims
To analyze: 1) the lipid profile in people with impaired fasting glucose (IFG) and 2) its potential association with clinical and metabolic parameters. Materials and methods: 101 people were recruited from those attending the University of Internal Medicine UNLP clinic, including people of both sexes, >15 years who sign informed consent to participate in the study; those treated with drugs that affect lipid metabolism and with type 2 diabetes were excluded. In all of them had we recoded body mass index (BMI), abdominal circumference (AC) and blood pressure. Their personal history, inherited relatives, life habits and occurrence of cardiovascular events were also recorded. In their blood samples, blood glucose, HbA1c and lipid profile were measured as well as insulin and HOMA-IR index in most of them. Statistical evaluation included ANOVA and Tukey’s test; significant differences were considered when their p value was ≤0.05.
Results
67.32% of the participants presented glycemias ≤100 mg/dl (control group) and 32.67% values compatible with IFG status. Mean age, BMI and WC, HbA1c, insulin and HOMA-IR values, as well as the percentage of people with hypertension, were significantly higher in the latter group. The values of the lipid profile recorded were higher in the GAA group except the HDL-c in which they were lower.
Conclusion
Since the dyslipidemia present in people with IFG would simultaneously be a marker of atherosclerosis obliterans and a promoter of the transition to DT2, it requires its early diagnosis and treatment.
Palabras clave : Dyslipidemia in prediabetes; Impaired fasting glucose; Dysglycemias; Insulin resistance.