Resumen

MAISA, Silva,; FERNANDA, Lima Margal,  y  MARIA, de Matos, lone. Animal venoms as possible therapeutic tools against oxidative stress in several diseases: Literature Review. Acta toxicol. argent. [online]. 2021, vol.29, n.2, pp.21-30. ISSN 1851-3743.

Venoms are a toxic substance (comprised of one or more toxins) that can cause dose-dependent physiological injury. Toxins are bioactive molecules formed primarily by enzymatic and non-enzymatic compounds that cause undesirable conse-quences in prey, in addition, exhibit unique, diverse and specific biological activities that disrupt normal physiological processes. However, many toxins, from different animals, have been isolated and many of them are considered great tools for basic research and therapeutic targets. Oxidative stress has been reported to play a key role in the pathogenesis of various diseases such as neurodegenerative disorders, cardiovascular disorders and cancer. How animal toxins act on oxidative stress parameters in several diseases is not yet established. The main focus of this review is to highlight the main studies with animal toxins as a therapeutic tool in several diseases, acting on the organism’s redox balance.

Palabras clave : Venom; Therapeutic tools; Oxidative stress; Antioxidants.

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