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Archivos argentinos de pediatría
versão impressa ISSN 0325-0075versão On-line ISSN 1668-3501
Resumo
CARGNEL, Elda G; CARDOSO, Patricia C; IRIGOYEN, Julián e GARCIA PUGLISI, Sol. An unintended diagnosis: Serotonergic toxicity secondary to drug interactions. Case reports. Arch. argent. pediatr. [online]. 2018, vol.116, n.1, pp.e115-e120. ISSN 0325-0075. http://dx.doi.org/10.5546/aap.2018.e115.
Serotonin toxicity is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. It is seen with therapeutic medication use, intentional self-poisoning and inadvertent interactions (SSRI-isoniazid). Although this pathology is increasingly common, it is not well recognized by physicians and manifestations may be wrongly attributed to another cause. The aim of this paper is to describe the clinical picture of a patient, to collaborate on diagnosis and to improve medical care of these patients.
Palavras-chave : Serotonin syndrome; Serotonergic agents; Isoniazid; Drug interactions.