Resumo

CANALEJO, Katia et al. Evaluation of the fraction of immature reticulocytes as a parameter of iron deficiency in pregnancy. Acta bioquím. clín. latinoam. [online]. 2011, vol.45, n.1, pp.81-85. ISSN 0325-2957.

Pregnant women constitute a group capable of developing iron deficiency anemia, which causes a disturbance of hematopoiesis, with increased reticulocyte mainly at the expense of the immature reticulocyte fraction (IRF). The aim of this work was to assess IRF sensitivity (S) and specificity (E for its name in Spanish) for early diagnosis of iron deficiency in pregnancy. Blood samples from 99 pregnant women who attended Vélez Sarsfield Hospital Laboratory for prenatal care. Complete blood cells and reticulocyte automated counts were performed and serum iron and ferritin were analyzed. A 0.35 IRF cutoff was taken when the ROC curve (receiver-operating characteristic curve) was evaluated and a 76.1% sensitivity and 53.1%. specificity were found. Comparison of hematological and biochemical parameters of the samples with IRF lower and higher than 0.35 shows significant differences (p<0.05). These results make it possible to recommend this test for early diagnosis of iron deficiency.

Palavras-chave : Pregnancy; Iron deficiency; Immature reticulocyte fraction; Sensitivity and specificity.

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