Resumo

SANTOLIN, Carolina et al. Rectal colonisation by multiresistant gram-negative bacilli: relevance of early detection in the course of hospitalization. Acta bioquím. clín. latinoam. [online]. 2017, vol.51, n.4, pp.675-680. ISSN 0325-2957.

Healthcare associated infections are considered an epidemic problem; manageable but difficult to eradicate. The early detection of patients infected with antimicrobial multiresistant microorganisms by means of epidemiological surveillance cultures and the execution of prophylactic measures, are key to reduce their incidence. The aim of this work was to assess a suitable schedule in the course of hospitalisation to perform colonisation studies and to decide which microorganisms to analyse according to the provenance of the patient. Rectal swabs from patients admitted at the Intensive Care Unit obtained at the time of admission, 72 h and six days later were analysed. Multiresistant Acinetobacter spp.(MRA), ESBL- and KPC- producing Enterobacteriaceae (ESBL-EB and KPC-EB, respectively) were investigated. Results showed that 15.2% of patients without previous hospitalisation and 16.7% of patients coming from geriatric institutions were colonised by ESBL-EB at the moment of admission. This percentage was greater (28.6%) in previously hospitalised patients, of whom 2.6% were found to be colonized by KPC-EB and 3.4% by MRA. Subsequent monitoring showed increasing colonisation percentages with the course of hospitalisation. Therefore, detection of these microorganisms at the time of admission and constant active surveillance are crucial to implement early measures aiming to avoid the consequences of rapid horizontal dissemination.

Palavras-chave : Epidemiologic surveillance; Rectal swabs; Extended-spectrum beta-lactamase producing Enterobacteriaceae; KPC- producing Enterobacteriaceae; Multiresistant Acinetobacter spp.

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