Resumo

EGANA ZUNZUNEGUI, Nerea et al. Central diabetes insipidus as the first sign of Langerhans cell histiocytosis in an adult. Rev. argent. endocrinol. metab. [online]. 2017, vol.54, n.1, pp.47-49. ISSN 1851-3034.

Langerhans cell histiocytosis is considered a paediatric disease, although it may be diagnosed in adults. The histiocyte infiltration in adults is most frequently in bones, lungs and skin, and shows a particular predilection for hypothalamus-pituitary axis. A case is presented of a 51 year-old man who initially only presented with central insipidus diabetes, and over time developed systemic disease with skin, lungs, bones, pituitary, and central nervous system involvement. Chemotherapy and radiotherapy were effective, and there is currently no progression of the disease.

Palavras-chave : Langerhans cell histiocytosis; Diabetes insipidus; Adult.

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