Abstract

SAENZ DE CHIRIFE, Ana María et al. Signet ing cell lymphoma mimicking mucin-producing carcinoma. Medicina (B. Aires) [online]. 2004, vol.64, n.6, pp.521-524. ISSN 0025-7680.

Signet ring cell lymphoma is a rare neoplasm caracterized by large, vacuolated and clear cells mimicking mucin-producing adenocarcinoma. It is localized in nodal and extranodal sites. A case of a 59 years old male, with a diffuse lymphoma signet ring cell type localized on oropharingeal mucosa is reported. The histopathology study showed signet ring cells and the immunophenotype was: vimentine(+), CD45(+), CD20(+), Ig M(+), Kappa chain(+) and high index proliferative activity of neoplastic cells (Ki 67:70%). After a review of the literature and previous reports, we could not find a similar case in this anatomic site. The patient had a unfavourable clinical course and died two months after the diagnosis without receiving any treatment.

Keywords : Signet ring cell lymphoma; Diffuse lymphoma with intracellular immunoglobulin; Oropharyngeal lymphoma.

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