Medicina (Buenos Aires)
versión On-line ISSN 1669-9106
COTORRUELO, Carlos et al. Alloimmunization to a high frequency Rh antigen. Medicina (B. Aires) [online]. 2006, vol.66, n.1, pp. 46-48. ISSN 1669-9106.
We report the case of a pregnant woman sensitized with a panreactive anti-Rh17 alloantibody. Patients red blood cells showed a partial deletion of Rh antigens, which was responsible for the alloimmunization. An autotransfusion program was instrumented so as to cover possible demands. Molecular analysis of the RH locus showed the presence of a hybrid RHCE-D(5-7)-CE allele that gave origin to the deleted phenotype.
Palabras llave : Rh system; alloantibody; hybrid allele.