Abstract

KLEINERT, María Mercedes et al. Reactive hemophagocytic syndrome in critical care patients: Report of 4 cases. Medicina (B. Aires) [online]. 2007, vol.67, n.1, pp.49-52. ISSN 0025-7680.

Reactive hemophagocytic syndrome or hemophagocytic lymphohistiocytosis comprises a  variety of disorders, many of them associated with infection. It is characterized by hemophagocytosis, with cytopenia involving at least two cellular lines, increase in cytokines and serum ferritin. The clinical course resembles sepsis, sharing similar physiopathological features. We propose that hemophagocytic syndrome is an underdiagnosed entity  in the critical care setting;  simple tests aid to identify which patients should undergo diagnostic procedures. We discuss current therapeutic approaches.

Keywords : Hemophagocytic syndrome; Hemophagocytic lymphohistiocytosis; Hemophagocitosis.

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