Medicina (Buenos Aires)
versión On-line ISSN 1669-9106
KLEINERT, María Mercedes et al. Reactive hemophagocytic syndrome in critical care patients: Report of 4 cases. Medicina (B. Aires) [online]. 2007, vol.67, n.1, pp. 49-52. ISSN 1669-9106.
Reactive hemophagocytic syndrome or hemophagocytic lymphohistiocytosis comprises a variety of disorders, many of them associated with infection. It is characterized by hemophagocytosis, with cytopenia involving at least two cellular lines, increase in cytokines and serum ferritin. The clinical course resembles sepsis, sharing similar physiopathological features. We propose that hemophagocytic syndrome is an underdiagnosed entity in the critical care setting; simple tests aid to identify which patients should undergo diagnostic procedures. We discuss current therapeutic approaches.
Palabras clave : Hemophagocytic syndrome; Hemophagocytic lymphohistiocytosis; Hemophagocitosis.