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Medicina (Buenos Aires)

Print version ISSN 0025-7680


EIZIKOVITS, Gabriela Y.; CASAL, Carolina; ARINI, Pedro D.  and  BERTRAN, Guillermo C.. Influence of sexual maturity and gonadectomy on cardiac electrical activity in male and female rabbits. Medicina (B. Aires) [online]. 2010, vol.70, n.4, pp.347-354. ISSN 0025-7680.

Sex-associated differences in cardiac electrical activity have already been documented. Even though these differences are usually associated with the effect of maturity and sex hormones, there are still some controversial points to this respect. The aim of this study was to evaluate the effects of maturity and gonadectomy on the different parameters of surface electrocardiogram and the duration of the action potential in young and adult rabbits. The differences obtained in females were observed in late repolarization, whereas in males took place in early repolarization. There was a relationship between the differences observed in the duration from the peak to the end of the T wave and those observed in the duration of the action potential to 90% of repolarization in females, whereas in males the relationship exists between the duration from the point J to the peak of the T wave and the duration of the action potential at 30 and 50% of repolarization. Differences could be related to hormonal or non-hormonal factors.

Keywords : Cardiac electrical activity; Sexual maturity; Sex hormones.

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