Abstract

RODRIGUEZ-REIMUNDES, Ezequiel; PERAZZO, Florencia  and  VILCHES, Antonio R.. Tumor lysis syndrome in a patient with a renal carcinoma treated with sunitinib. Medicina (B. Aires) [online]. 2011, vol.71, n.2, pp.158-160. ISSN 0025-7680.

The tumor mor lysis syndrome (TLS) is a metabolic disorder resulting from a massive tumor breakdown. It is characterized by hyperuricemia, hyperphosphatemia, hypocalcemia and hyperkalemia and predisposes to acute renal failure. TLS usually occurs after the initiation of cytotoxic therapy and is more frequent in the case of neoplasias with a high proliferative rate or that are highly chemo-sensitive. We report the case of a man with a recurrent kidney cancer who presented with a TLS and acute renal failure after initiation of sunitinib.

Keywords : Tumor lysis syndrome; Sunitinib; Acute renal failure.

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