Abstract

SERRA, Héctor A.; ROGANOVICH, Juan Manuel  and  RIZZO, Leonardo F. L.. Glucocorticoids: examples of translational medicine; from molecular aspects to bedside. Medicina (B. Aires) [online]. 2012, vol.72, n.2, pp.158-170. ISSN 0025-7680.

Glucocorticoids are anti-inflammatory, immunosuppressant and anti-allergic drugs derived from hydrocortisone. Their widespread use was originated from Hench's observations in patients with rheumatoid arthritis. These drugs are examples of translational medicine and they can be envisaged as one of the most prescribed and feared drugs. The objective of this review is to highlight their pharmacological properties and thus, allow a more suitable prescription.

Keywords : Glucocorticoids; Steroidal anti-inflammatory drugs; Clinical pharmacology; Therapeutic use of drugs.

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