Abstract

GIONO, Luciana E. CRISPR/Cas9 y la terapia génica. Medicina (B. Aires) [online]. 2017, vol.77, n.5, pp.405-409. ISSN 0025-7680.

The development of techniques that allow the precise and efficient edition of the genome of living cells is one of the main goals of biomedical research. Over the last few decades, a number of genome editing tools have been developed, the most prominent being the CRISPR/Cas9 system, a bacterial defense mechanism that has been redesigned for its use in other cellular systems. The accessibility, both technical and economical, and the enormous potential of CRISPR/Cas9 have contributed to an almost unprecedented revolution in the biomedical sciences and represent an important step forward in the field of gene therapy that needs, however, to be taken cautiously.

Keywords : CRISPR/Cas9; Genome editing; Gene therapy; Human embryos.

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