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Medicina (Buenos Aires)

Print version ISSN 0025-7680On-line version ISSN 1669-9106

Abstract

ZULFIQAR, Abrar-Ahmad; ANDRES, Emmanuel  and  VILLALBA, Noel Lorenzo. Hipervitaminosis B12: Nuestra experiencia y una revisión. Medicina (B. Aires) [online]. 2019, vol.79, n.5, pp.391-396. ISSN 0025-7680.

High serum levels of vitamin B12 or cobalamin, also called hypervitaminemia B12, is a frequently underestimated biological abnormality. According to the literature, some of the entities related to this finding are solid neoplasia (primary or metastatic) and acute or chronic hematological diseases. Other causes include liver disorders, monoclonal gammapathy of undetermined significance, renal failure and, less frequently, excess of vitamin B12 intake, inflammatory or autoimmune diseases, and transient hematological disorders (neutrophilia and secondary eosinophilia). This article reports on causes of hypervitaminosis B12, our experience and a review of the literature.

Keywords : Cobalamin; B12 hypervitaminemia; Transcobalamin; Hematological malignant disease; Neoplasia.

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