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Medicina (Buenos Aires)

Print version ISSN 0025-7680On-line version ISSN 1669-9106


CROCCI, Eric E. et al. Características de las infecciones causadas por Corona virus humanos endémicos durante la pandemia COVID-19. Medicina (B. Aires) [online]. 2024, vol.84, n.1, pp.102-107. ISSN 0025-7680.


: After the implementation of mitigation strategies during the COVID-19 pandemic, the incidence of respiratory viruses, including human coronaviruses (HCoV), experienced a significant decrease. The aim of this study is to characterize the epidemiology and clinical aspects of HCoV infections in ambulatory adults during COVID-19 pandemic times.


: descriptive, prospective, longitudinal study performed in a private hospital in La Plata, Buenos Aires, Argentina between November 2020 and October 2022; 458 outpatient adults with upper respiratory tract infections (URTI) were studied undergoing clinical and microbiological follow-up.


: 44 (9.6%) subjects were positive by multiplex PCR for HCoV. 14 of them for 229E (31.8%), 13 for OC43 (29.5%), 11 for HKU-1 (25.1%) and 6 for NL63 (13.6%). A repeated PCR was positive for the same HCoV in 19 (57%) of 33 patients on day 3-5. No hospitalizations or deaths were reported.


: Endemic HCoV caused a significant pro portion of URTI among outpatient adults during COVID- 19-related restrictions times. An alternating pattern of circulation between alfa-HCoV and beta-HCoV was observed.

Keywords : Human coronaviruses; Respiratory tract infections; COVID-19 pandemic; Alphacoronavirus; Beta coronavirus; Coronavirus humanos; Infecciones de vía aérea superior; Pandemia COVID-19; Alphacoronavirus; Betacoronavirus.

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