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Archivos argentinos de pediatría

Print version ISSN 0325-0075


CIOCCA, Mirta  and  ALVAREZ, Fernando. Transient neonatal cholestasis. Arch. argent. pediatr. [online]. 2011, vol.109, n.2, pp.163-166. ISSN 0325-0075.

Due to immaturity of mechanisms involved in bile formation, the newborn is more susceptible to develop cholestasis. The causes of neonatal cholestasis are: infection, genetic and metabolic diseases, biliary atresia, and unknown or idiopatic etiologies. Most patients in whom no etiology is found are considered to belong to the group of transient neonatal cholestasis by some authors. Transient neonatal cholestasis is characterized by: early-onset cholestasis, absence of a known cause of neonatal cholestasis, normalization of clinical and biochemical parameters during follow-up, and a history of some neonatal injurious event (asphyxia, sepsis, total parenteral nutrition, etc.).

Keywords : Cholestasis; Newborn.

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