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Archivos argentinos de pediatría

Print version ISSN 0325-0075


EIMER, Lena et al. Darier-White disease treated with oral isotretinoin. Arch. argent. pediatr. [online]. 2011, vol.109, n.4, pp.e63-e66. ISSN 0325-0075.

Darier-White Disease (DWD) is an autosomal dominant disorder, described by Darier and White in 1889, characterized by abnormal keratinization in the epidermis, nails and mucosae. We present the case of a 16-year-old, male patient, with clinically and histologically confrmed DWD treated with oral isotretinoin (0.7 mg/kg/day) for six months, with good response. We recommend an optional therapeutic treatment for chronic, itchy, recalcitrant lesions with oral retinoids.

Keywords : Darier-White disease; Therapy; Oral retinoids; Oral isotretinoin.

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