Abstract

LOPEZ, Mariela et al. Validation of a simplified prediction rule to identify etiology in children with pneumonia. Arch. argent. pediatr. [online]. 2011, vol.109, n.6, pp.499-503. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2011.499.

Introduction. Identifying on admission those children with bacterial pneumonia could reduce inappropriate antibiotic use. The BPS (Bacterial Pneumonia Score) is a clinical prediction rule that accurately identifes children with bacterial pneumonia. Because the interpretation of chest X-ray included in this model could be considered diffcult, a simplifed version was developed, but this version has not yet been validated in a different population. Objective. To validate a simplifed clinical prediction rule to identify children with an increased risk of having bacterial pneumonia. Methods. Children aged under 5 years, hospitalized for pneumonia (viral or bacterial) were included. On admission, axillary temperature, age, absolute neutrophil count, bands, and chest radiograph were evaluated. Results. We included 168 patients (23 with bacte­rial pneumonia and 145 with viral pneumonia). Those with bacterial pneumonia showed a score higher than those with viral pneumonia (5.3 ± 2.5 vs. 2.6 ± 2.02; p <0.001). A score =3 points was identifed as the optimum cutoff value to predict bacterial pneumonia (aucROC= 0.79; 95% IC: 0.68-0.90), and was more frequent among patients with bacterial than viral pneumonia (19/23 vs. 42/145, p= 0.003; OR: 4.8; CI95%: 1.4-17.6), achieving 82.6% sensitivity, 50.3% specifcity, 20.9% positive predictive value, 94.8% negative predictive value, 1.66 positive likelihood ratio and 0.35 negative likelihood ratio. Conclusions. The evaluated simplifed prediction rule showed a limited diagnostic accuracy on identifying children with bacterial pneumonia, being less accurate than the BPS.

Keywords : Pneumonia; Respiratory tract infection; Diagnosis; Differential.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )