Abstract

MALLA, Ivone; PEREZ, Celeste; CHEANG, Yu  and  SILVA, Marcelo. Human herpesvirus 8 related Kaposi's sarcoma in a pediatric liver transplant recipient: Case report. Arch. argent. pediatr. [online]. 2013, vol.111, n.5, pp.450-453. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2013.e125.

Patients under immunosuppressive treatment are at risk of developing malignant tumors. Primary infection or reactivation of human herpesvirus 8 (HHV-8) may predispose to Kaposi's sarcoma (KS) after solid organ transplantation. KS in pediatric liver transplant recipients has low incidence and poor prognosis. We report the clinical presentation of a KS in lymph node following HHV-8 infection in a pediatric patient presenting four months after liver transplantation. He had a good outcome with suspension of tacrolimus and conversion to sirolimus one month after diagnosis. To our knowledge, this is the frst KS reported case in our country after liver transplant in a pediatric recipient and we believe that this entity should be taken into consideration in the differential diagnosis of post-transplant complications.

Keywords : Liver transplantation; Pediatrics; Human herpesvirus 8; Malignancy; Kaposi sarcoma.

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