Abstract

MORENO, Laura et al. Human bocavirus respiratory infection in infants in córdoba, Argentina. Arch. argent. pediatr. [online]. 2014, vol.112, n.1, pp.70-74. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2014.70.

It has been suggested that human bocavirus (HBoV) is related to acute respiratory infection (ARI) in children (prevalence: 0.9% to 33%) although clinical characteristics have not been clearly established yet. Objectives. To identify the presence of HBoV in patients with ARI hospitalized in Hospital de Niños de Córdoba and describe cases without co-infection. Method. HBoV screening was done by traditional PCR. Specimens to be screened were obtained from nasal secretions of 222 children under 2 years of age hospitalized due to an ARI during 2011. Demographic, clinical and radiological data were recorded. Results. Fifteen HBoV+ patients (6.8%) were identifed. Their median age was 3.5 months (range: 1-22), 7/15 in co-infection (5 respiratory syncytial virus, 1 parainfuenza-3, 1 Bordetella pertussis). Cases without co-infection: pneumonia 5/8, bronchiolitis 3/8; two required intermediate care, 7/8 oxygen therapy, 7/8 bronchodilators, 6/8 antibiotics; associated disease 1/8 (microcephalus/heart disease). Conclusions. HBoV was identifed in 15 out of 222 children (6.8%); the diagnosis of pneumonia was predominant without severe cases nor complications upon discharge.

Keywords : Human bocavirus; Acute respiratory infection; Pneumonia; Infants.

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