Abstract

CABANILLAS, Diana; D'ALESSANDRO, Virginia; DIEZ, Graciela  and  REGAIRAZ, Lorena. Specific antibody deficiency: cases serie. Arch. argent. pediatr. [online]. 2014, vol.112, n.6, pp.e247-e251. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2014.e247.

Specific antibody deficiency is a common antibody immunodeficiency defined as a poor antibody response to pneumococcal polysaccharides antigens present in the 23-valent pneumococcal vaccine, with normal immunoglobulins and normal response to protein antigens. Clinical manifestations include recurrent sinopulmonary infections, severe infections and asthma. The aim of this presentation is to describe clinical manifestations and evolution of a cohort of children with specific antibody deficiency diagnosed and followed in our center between 1998 and 2012.

Keywords : Immunodeficiency; Respiratory infections; Polysaccharide antibody response failure.

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