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Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501


LUONG, Tai C et al. Langerhans cell histiocytosis with vertebral involvement and soft tissue extension: Clinical case. Arch. argent. pediatr. [online]. 2016, vol.114, n.4, pp.e256-e259. ISSN 0325-0075.

Langerhans cell histiocytosis is a heterogeneous disease of unknown etiology characterized by proliferation of Langerhans cells. It is a rare disease. Bone involvement is common but vertebral disease is rare. We present a 4 year old patient with abdominal pain and neurologic symptoms. Magnetic resonance showed vertebra plana in D9 with involvement of paravertebral soft tissues. The child underwent surgery for decompression and biopsy. Biopsy confirmed Langerhans cell histiocytosis. She was treated with vinblastine and prednisone during 6 months following LCH-III with complete recovery of neurologic symptoms. Conclusion. Langerhans cell histiocytosis is a differential diagnosis in a radiograph with vertebra plana or collapse of vertebral body.

Keywords : Langerhans cell histiocytosis; Spinal diseases; Vertebra plana.

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