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Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501


DIAZ ANGARITA, Tomás et al. Systemic sarcoidosis: a diagnostic challenge in pediatrics. Case report. Arch. argent. pediatr. [online]. 2016, vol.114, n.5, pp.e323-e328. ISSN 0325-0075.

Sarcoidosis is a granulomatous inflammatory disease of unknown etiology, evidenced most often in young adults, which can compromise several organs, mainly lung, lymph nodes, eyes and skin. The presence of the disease in pediatric population is rare. Denomination in pediatrics is made based on age and clinical manifestations of the patient. The aim of this report is to present a case of systemic sarcoidosis in a pediatric patient without lung involvement with severe extrapulmonary manifestations. Fifteen year old patient who debuted with nonspecific symptoms (emesis, weight loss). Radiographic studies without lung involvement but with findings suggestive of Langerhans cell histiocytosis; however, histopathological report (bone and lymph) showed the presence of chronic granulomatous nonnecrotizing disease, sarcoidosis type. Childhood sarcoidosis is a rare and difficult entity to diagnose, mainly by the lack of specific biomarkers for diagnosis.

Keywords : Sarcoidosis; Pulmonary disease; Child; Diagnosis.

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