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Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501

Abstract

LALIENA AZNAR, Sara et al. Gestational alloimmune liver disease: a case report. Arch. argent. pediatr. [online]. 2016, vol.114, n.6, pp.e408-e412. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2016.e408.

Gestational alloimmune liver disease, previously known as neonatal hemochromatosis, is characterized by severe liver disease in neonatal period, associated with intra and extrahepatic iron accumulation. It is postulated an alloimmune origin, which has opened new opportunities in the treatment and prevention during risk pregnancies, changing the prognosis of this pathology. We report the case of a newborn that presents early liver failure, with clinical and analytical features compatible with gestational alloimmune liver disease. Exchange transfusion was made and gamma globulins were given, with good clinical evolution.

Keywords : Hemochromatosis; Neonatal liver disease; Congenital alloimmune hepatitis; Liver failure.

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