SciELO - Scientific Electronic Library Online

vol.115 issue2Paradoxical reaction to antituberculosis treatment in an immunocompetent girl with pulmonary tuberculosisSubglottic stenosis as the initial manifestation of Wegener's granulomatosis in a teenager: Case report author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501


ALPEROVICH, Ruth et al. Generalized eruptive histiocytosis-Juvenile xanthogranuloma: clinical spectrum in a pediatric patient. Arch. argent. pediatr. [online]. 2017, vol.115, n.2, pp.e116-e119. ISSN 0325-0075.

Both, generalized eruptive histiocytosis and juvenile xanthogranuloma are dendritic histiocytic disorders (also known as non-Langerhans cells histiocytosis) that share clinicopathological and immunohistiochemical characteristics. We present a 3-year-old female patient with skin lesions that were clinically compatible with generalized eruptive histiocytosis, confirmed by histopathological and immunohistochemical studies. During her development the disorder compromised the central nervous system, and surgical intervention of one symptomatic lesion was needed. The histopathological exam of the central nervous system lesion showed Touton cells, compatible with a diagnosis of juvenile xanthogranuloma. This case demonstrates the need to consider these diseases as a spectrum of the same entity.

Keywords : Histiocytosis; Generalized eruptive histiocytosis; Xanthogranuloma juvenile.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License