SciELO - Scientific Electronic Library Online

 
vol.115 issue4Association between dietary glycemic load and metabolic syndrome in obese children and adolescentsEffects of 25 hydroxy vitamin D levels on the severity and asthma control in school age asthma patients author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501

Abstract

PETRIZ, Natalia A et al. Natural history of immunoglobulin E-mediated cow's milk allergy in a population of Argentine children. Arch. argent. pediatr. [online]. 2017, vol.115, n.4, pp.331-335. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2017.331.

Introduction. Cow's milk protein allergy is the most common allergy in pediatrics. Immunoglobulin E (IgE)-mediated cow's milk allergy poses a higher risk for life and a worse prognosis. Objectives. To describe the course of IgE-mediated cow's milk protein allergy and risk factors associated with disease persistence. Patients and methods. This was a descriptive, retrospective study conducted in patients seen at the Division of Pediatric Allergy of Hospital Italiano between June 2006 and June 2012 who had been diagnosed with IgE-mediated cow's milk allergy. Results. Out of the 72 patients with IgE-mediated cow's milk allergy, 39 (54%) were boys. Patients' average age at the time of diagnosis was 5.19 ± 3.7 months old; the most common symptoms were urticaria and vomiting. Rhinitis and asthma were the most commonly observed concomitant atopic diseases. In the study period, 54.5% of patients developed tolerance at an average age of 32 months old. An 8-mm papule in the skin prick test and casein sensitization were associated with disease persistence. Conclusion. Overall, 54.5% of patients developed tolerance at 32 months old. A significant association was observed between papule size at the time of diagnosis and casein sensitization and disease persistence.

Keywords : Allergy; Milk; Immunoglobulin E; Natural history.

        · abstract in Spanish     · text in Spanish     · English ( pdf ) | Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License