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Archivos argentinos de pediatría

Print version ISSN 0325-0075On-line version ISSN 1668-3501


CARGNEL, Elda G; CARDOSO, Patricia C; IRIGOYEN, Julián  and  GARCIA PUGLISI, Sol. An unintended diagnosis: Serotonergic toxicity secondary to drug interactions. Case reports. Arch. argent. pediatr. [online]. 2018, vol.116, n.1, pp.e115-e120. ISSN 0325-0075.

Serotonin toxicity is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. It is seen with therapeutic medication use, intentional self-poisoning and inadvertent interactions (SSRI-isoniazid). Although this pathology is increasingly common, it is not well recognized by physicians and manifestations may be wrongly attributed to another cause. The aim of this paper is to describe the clinical picture of a patient, to collaborate on diagnosis and to improve medical care of these patients.

Keywords : Serotonin syndrome; Serotonergic agents; Isoniazid; Drug interactions.

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