Abstract

ASTOLFO, Ma. Florencia et al. Invasive acute sinusitis by Exserohilum rostratum in a patient with medullary relapse of acute lymphoblastic leukemia. Arch. argent. pediatr. [online]. 2018, vol.116, n.4, pp.e594-e598. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2018.e594.

Invasive fungal infection has increased in frequency over the last decade, with fungal sinusitis becoming more frequent. The fungi of the genus Exserohilum (family Pleosporaceae, order Pleosporales) are filamentous and dematiaceous of ubiquitous location. It is an emerging pathogen, which in most cases produces a systemic infection that mainly affects the paranasal sinuses and lungs. It is more common in immunosuppressed patients, although it may occur in immunocompetent patients. The treatment is based on three pillars: antifungal treatment, surgical debridement and restitution of immunity. We present the case of a patient with medullary relapse of acute lymphoblastic leukemia with invasive fungal sinusitis by Exserohilum rostratum.

Keywords : Exserohilum rostratum; Sinusitis; Invasive fungal infections; Leukemia; Immunosuppression.

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