Abstract

GARCIA-SALIDO, Alberto et al. Coinfection by astrovirus and Neisseria B meningitidis in a girl. Arch. argent. pediatr. [online]. 2018, vol.116, n.5, pp.e659-e662. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2018.e659.

Meningococcal infection associates high morbidity and mortality. Viral coinfection has been described mainly with herpes and respiratory virus. We describe a child who suffered a tonic-clonic seizure with hypotension, tachycardia and low Glasgow Coma Scale. She maintained an altered mental status and required hemodynamic stabilization in the Pediatric Intensive Care Unit. Wide spectrum antibiotherapy was initiated. She suffered large and foul-smelling liquid not bloody stools which were cultured and studied by polymerase chain reaction. The cerebrospinal fluid was normal. Later the polymerase chain reaction stools were positive to astrovirus, and the blood polymerase chain reaction was positive to Neisseria meningitidis group B. As far as we know, this is the first case of astrovirus and Neisseria meningitidis coinfection described in children. This virus should be considered as new cause of viral coinfection to discard if unexplained abdominal pain or vomits and liquid stools are observed.

Keywords : Neisseria meningitidis serogroup B; Astrovirus; Gastroenteritis; Seizure; Sepsis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )