Abstract

SERRANO VINUALES, Itziar et al. Postinfectious rapidly progressive glomerulonephritis in a pediatric patient. Arch. argent. pediatr. [online]. 2019, vol.117, n.4, pp.e363-e367. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2019.e363.

Postinfectious glomerulonephritis is rarely presented as rapidly progressive glomerulonephritis in children; the prevalence is approximately 1-3 %. Most children have acute onset of renal failure; initial treatment involves corticosteroids and immunosuppressive therapy. Early diagnosis improves prognosis. In recent years, an entity known as "C3 glomerulopathies" has been described, presenting characteristics that overlap. In the differential diagnosis, the immunofluorescence and the determination of the nephritic factor are useful. We report a 4-year-old boy with fever, respiratory symptoms and hyporexia. Microhematuria, proteinuria, decline in glomerular filtration and depressed C3 were found. Acute glomerulonephritis was suspected. Renal biopsy showed crescent formation, immunofluorescence staining for C3 and subepithelial humps. Therefore, postinfectious glomerulonephritis with crescent formations was diagnosed.

Keywords : Rapidly progressive glomerulonephritis; Postinfectious; Corticoids; Immunosuppressive agents; Pediatrics.

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