Abstract

PERUFFO, María V et al. Distant bacillus Calmette-Guérin disease in an infant: Case report. Arch. argent. pediatr. [online]. 2019, vol.117, n.5, pp.e497-e501. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2019.e497.

The bacillus Calmette-Guérin vaccine is an attenuated vaccine historically used to prevent severe forms of tuberculosis. It is applied to all newborns in countries with high prevalence of tuberculosis. Local complications, such as suppuration or regional adenopathies, may occur after application. Disease due to the spread of the bacillus is infrequent, usually occurring in a patient with an underlying immune alteration. We present the case of a 5-month-old child who was admitted due to a 2-month evolution with weight loss and subcutaneous nodules. Disease was suspected to be due to bacillus Calmette-Guérin dissemination, being diagnosed by biopsy of the lesions. Treatment was carried out with three antituberculous drugs, evolving towards clinical recovery. Although immunological studies were carried out, no immunodeficiency could be demonstrated as a predisposing condition.

Keywords : BCG; Disseminated BCG; Bacillus Calmette-Guérin disease; Congenital immunodeficiency.

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