Abstract

DUJOVNE, Noelia V et al. Predictive outcome measures of adult short stature in patients with severe acquiredautoimmune hypothyroidism. Arch. argent. pediatr. [online]. 2019, vol.117, n.6, pp.388-388.  Epub Dec 01, 2019. ISSN 0325-0075.  http://dx.doi.org/10.5546/aap.2019.388.

Hypothyroidism caused by Hashimoto's thyroiditis is the most common reason for thyroiddysfunction in children. Our objective was to analyze its impact on final stature in relation to height and pubertalstage at the time of diagnosis in childrenyounger than 18 years with severe autoimmunehypothyroidism. Out of 79 patients, 78.5 %were girls. Those with goiter (56 %) had a betterheight at diagnosis than those without goiter (mean standard deviation score for height: 0.2 versus -2.42; p < 0.0001). Five girls (6.3 %) had precocious puberty. When considering the finalstature of patients (n: 33), among those with shortstature at the time of diagnosis, pubertal childrenhad a significantly shorter final stature thanprepubertal children (mean standard deviationscore for height: -2.82 versus -1.52; p = 0.0311). The late diagnosis of severe hypothyroidism inpediatrics has a negative impact on final stature, especially in those who were pubertal patientsat the time of diagnosis.

Keywords : Hypothyroidism; Hashimoto's thyroiditis; Stature; Precocious puberty.

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