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Archivos argentinos de pediatría
Print version ISSN 0325-0075On-line version ISSN 1668-3501
Abstract
OKUR, Nilufer et al. Neonatal pain and heart rate variability in preterm infants treated with surfactant: a pilot study. Arch. argent. pediatr. [online]. 2019, vol.117, n.6, pp.397-397. Epub Dec 01, 2019. ISSN 0325-0075. http://dx.doi.org/10.5546/aap.2019.397.
Objective
We aimed to assess the pain perception of preterm infants treated with different surfactant administrationtechniques by using heart rate variability (HRV).
Methods
Preterm infants who required surfactant therapy for RDS were randomized to INSURE or MIST groups. HRV analysis was performed by Newborn Infant Parasympathetic Evaluation monitor. HRV was recorded before, during and aftersurfactant administration. Pain assessment was determined by Premature Infant Pain Profile (PIPP) score.
Results
Fourteen infants were enrolled in the study. Demographic characteristics of the groups were similar. PIPP scores did not differ between INSURE and MIST groups (p = 0.05). Statistically significant difference in median HRV during surfactant administration was observed between INSURE and MIST groups (52 vs. 56, p = 0.03). HRV analysiswas similar between groups before and after surfactantadministration.
Conclusion
Surfactant administration with MIST technique might be more comfortable for preterm infants with RDS. However further studies with larger series are needed.
Keywords : Intubation; Premature infant; Pain; Pulmonary surfactant.
