SciELO - Scientific Electronic Library Online

 
vol.41 número2Perfil hematológico de la beta-talasemia menor en TucumánDeterminación y estandarización de plomo en sangre en operarios de estaciones de servicio del Estado Mérida índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Bookmark


Acta bioquímica clínica latinoamericana

versión On-line ISSN 1851-6114

Resumen

PONCE DE LEON, Patricia; FORESTO, Patricia  y  VALVERDE, Juana. Ascaris lumbricoides: Inhibitory capacity in relation to P1 antigen. Acta bioquím. clín. latinoam. [online]. 2007, vol.41, n.2, pp. 225-228. ISSN 1851-6114.

P Blood Group has a unique antigen: P1. It was identified in various parasite species. The aim of this work was to determine A. lumbricoides´s Inhibitory Capacity in relation to P1 antigen. The work was based on 11 parasite extracts (AE). The semiquantitative inhibition agglutination technique was used to assess the extracts´ Inhibitory Capacity in relation to P1 antigen. Two series of anti- P1 monoclonal antibody dilutions were prepared. PBS was added to the first series and an equal volume of AE to the second. Suspensions of P1 red cells were used as a revealing system. Monoclonal antibody titres were determined in both series. The agglutination was considered significative when there was a difference of two or more dilutions between the titres. Eight of the 11 extracts studied presented P1 epithopes. Inhibitory power of these 8 extracts was calculated and it was related with their protein concentrations to compare the Inhibitory Capacity among the extracts. The technique used made it possible to prove P System epithopes presence and to compare the extracts´ Inhibitory Capacity in relation to P1 epithopes.

Palabras llave : Ascaris lumbricoides; inhibitory capacity; P1 antigen.

        · resumen en Español     · texto en Español     · pdf en Español