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Acta bioquímica clínica latinoamericana

versión On-line ISSN 1851-6114


GUERRA-LOPEZ, José Rodolfo; GUIDA, Jorge Alberto; DELLA VEDOVA, Carlos Omar  y  GARCIA, Roberto Ricardo. Renal stone characterization by infrared spectroscopy. Acta bioquím. clín. latinoam. [online]. 2008, vol.42, n.2, pp. 189-193. ISSN 1851-6114.

This work confirms that infrared spectroscopy is a powerful technique to detect renal calculi components. The studied calculi are composed mainly of oxalate and phosphate mixture as well as oxalate mixture. Special interest was centered in oxalate calculi because of the likely presence of different phases, which should be difficult to detect by other techniques. To improve the identification of the different phases present in calculi the second derivative spectra were used. The FTIR spectroscopic together with the second derivative analysis allows the urologist to have a good method for calculi component determinations. Consequently, in accordance with its composition correctly correlated with specific pathophysiologycal conditions it provides the urologist with important information about calculus treatment. The objective of this paper is to contribute to establish such relation.

Palabras clave : Infrared spectroscopy; Second derivative spectra; Wedellite; Wewellite, calcium phosphate; Carbonate apatite; Urinary calculi; Pathophysiological conditions.

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